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Noninvasive ventilation (NIV), also known as noninvasive positive pressure ventilation (NPPV), is an effective treatment for ventilatory failure,1-2 including Paediatric cases.3
For patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) the use of NPPV is associated with:4-9
While of limited benefit for the long-term treatment of COPD patients, domiciliary NPPV might be beneficial in COPD patients with hypercapnia.10-12
NPPV is an important part of disease management for patients with advanced neuromuscular disease and chest wall disorders. NPPV is usually initiated if there are symptoms due to nocturnal hypoventilation or right heart failure in the presence of a raised carbon dioxide tension in arterial blood.13-14 NPPV is a highly cost-effective treatment for appropriate patients.15-16
BTS Standards of Care Committee. Non-invasive ventilation in acute respiratory failure
Chin K, Uemoto S, Takahashi K, Egawa H, Kasahara M, Fujimoto Y, Sumi K, Mishima M, Sullivan CE, Tanaka K. Noninvasive ventilation for Paediatric patients including those under 1-year-old undergoing liver transplantation.
Ram F, Picot J, Lightowler J, Wedzicha J. Non-invasive positive pressure ventilation for treatment of respiratory failure due to exacerbations of chronic obstructive pulmonary disease.
Girou E, Brun-Buisson C, Taille S, Lemaire F, Brochard L. Secular trends in nosocomial infections and mortality associated with noninvasive ventilation in patients with exacerbation of COPD and pulmonary edema.
Conti G, Antonelli M, Navalesi P, Rocco M, Bufi M, Spadetta G, Meduri GU. Noninvasive vs. conventional mechanical ventilation in patients with chronic obstructive pulmonary disease after failure of medical treatment in the ward: a randomized trial.
Plant PK, Owen JL, Elliott MW. Early use of non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease on general respiratory wards: a multicentre randomised controlled trial.
Wijkstra PJ, Lacasse Y, Guyatt GH, Goldstein RS. Nocturnal non-invasive positive pressure ventilation for stable chronic obstructive pulmonary disease.
Jones SE, Packham S, Hebden M, Smith AP. Domiciliary Nocturnal Intermittent Positive Pressure Ventilation in Patients with Respiratory Failure Due to Severe COPD: Long Term Follow-up and Effect on Survival.
Perrin C, Unterborn JN, Ambrosio CD, Hill NS. Pulmonary complications of chronic neuromuscular diseases and their management.
Shneerson JM, Simonds AK. Noninvasive ventilation for chest wall and neuromuscular disorders.
Plant PK, Owen JL, Parrott S, Elliott MW. Cost effectiveness of ward based non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease: economic analysis of randomised controlled trial.
Keenan SP, Gregor J, Sibbald WJ, Cook D, Gafni A. Noninvasive positive pressure ventilation in the setting of severe, acute exacerbations of chronic obstructive pulmonary disease: more effective and less expensive.
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