What to consider before using a mouth guard
When considering a MAD or TRD for sleep apnea, it’s important to research treatment effectiveness, cost and other factors.
Effectiveness and treatment outcomes
Many people considering sleep apnea mouth guards want to know if they can replace continuous positive airway pressure (CPAP) therapy. Deciding on a treatment can vary based on many factors and should be made with a doctor.
Studies have compared health outcomes between CPAP and MAD use in obstructive sleep apnea (OSA) treatment. CPAP is widely recognized as the first-line therapy, particularly for patients with complex comorbidities.7 MADs, on the other hand, are often associated with higher adherence rates.5
One study found that after two years, both MADs and CPAP were effective in treating sleep apnea. However, CPAP worked better at helping people get more oxygen while they sleep and at reducing how often their breathing stops or becomes shallow.9
Diagnosis and getting started
Oral appliances can sometimes be used to treat obstructive sleep apnea (OSA). OSA is diagnosed with a sleep test — either at home or overnight in a lab. After taking a sleep test, you and your doctor can review the results and, if diagnosed with OSA, determine the best treatment option.
If you and your doctor determine that an oral appliance is appropriate, a dentist will take dental impressions. This can be done with a physical mold or digital scans. The goal is to determine how far forward your jaw needs to move to support comfort and effective OSA treatment.
Next, a custom oral device is made. During fittings, the device is adjusted to fine-tune your jaw position. Once you start sleeping with your mouth guard, you’ll want to follow up with your dentist. During these check-ins, your dentist can make sure your device is properly fitted and effectively treating your OSA.
Side effects and comfort considerations
The most common side effect when using an oral appliance for sleep apnea can be mild discomfort. That may include jaw soreness, tenderness in the mouth, dry mouth or excessive salivation. Often, these minor irritations only occur in the first few weeks as people get used to the mouth guard.10
Long-term issues are rare but can include tooth movement, ongoing discomfort in the jaw and changes in your bite.10 Regular follow-ups with your dentist can help catch these problems early. Adjustments to the device can support a comfortable fit and encourage consistent use.
People who use sleep apnea mouth guards tend to have better experiences when the devices fit properly and are comfortable. Regular follow-ups can help fine-tune the device’s fit and address any discomfort or changes.
Mouth guards as part of comprehensive obstructive sleep apnea treatment
Mouth guards and CPAP are not used together at the same time. But mouth guards and other therapies like positional therapy or weight management strategies can be used together.
Because obstructive sleep apnea (OSA) can evolve over time, follow-ups are needed to ensure treatment is still efficiently reducing the frequency of breathing pauses during sleep. They can help check whether a mouth guard is effectively controlling symptoms and provide data that guides necessary adjustments.
If you’re ready to learn more about your sleep health, take our sleep assessment today.
References
- Source: Johal Ama et al Ready-Made Versus Custom-Made Mandibular Repositioning Devices in Sleep Apnea A Randomized Clinical Trial Journal of Clinical Sleep Medicine JCSM Official Publication of the American Academy of Sleep Medicine vol 13 no 2 Feb 2017 pp 175–82 PubMed https://doi.org/10.5664/jcsm.6440
- Source: Cao Michelle T et al Continuous Positive Airway Pressure Therapy in Obstuctive Sleep Apnea Benefits and Alternatives Expert Review of Respiratory Medicine vol 11 no 4 Apr 2017 pp 259–72 PubMed https://doi.org/10.1080/17476348.2017.1305893
- Source: Knauert Melissa et al Clinical Consequences and Economic Costs of Untreated Obstructive Sleep Apnea Syndrome World Journal of Otorhinolaryngology Head and Neck Surgery vol 1 no 1 Sept 2015 pp 17–27 PubMed https://doi.org/10.1016/j.wjorl.2015.08.001
- Source: Kerner Nancy A and Steven P Roose Obstructive Sleep Apnea Is Linked to Depression and Cognitive Impairment Evidence and Potential Mechanisms The American Journal of Geriatric Psychiatry Official Journal of the American Association for Geriatric Psychiatry vol 24 no 6 June 2016 pp 496–508 PubMed Central https://doi.org/10.1016/j.jagp.2016.01.134
- Source: Resmeds 2025 Global Sleep Survey https://sleepsurvey.resmed.com/
- Source: Vecchierini Marie Françoise et al Mandibular Advancement Device Use in Obstructive Sleep Apnea ORCADES Study 5 Year Follow up Data Journal of Clinical Sleep Medicine JCSM Official Publication of the American Academy of Sleep Medicine vol 17 no 8 Aug 2021 pp 1695–705 PubMed https://doi.org/10.5664/jcsm.9308
- Source: Understanding Pap 2021 Division of Sleep Medicine at Harvard Medical School https://sleep.hms.harvard.edu/education-training/public-education/sleep-and-health-education-program/sleep-health-education-37
- Source: Basyuni Shadi et al An Update on Mandibular Advancement Devices for the Treatment of Obstructive Sleep Apnoea Hypopnoea Syndrome Journal of Thoracic Disease vol 10 no Suppl 1 Jan 2018 https://doi.org/10.21037/jtd.2017.12.18
- Source: Doff Michiel H J et al Oral Appliance Versus Continuous Positive Airway Pressure in Obstructive Sleep Apnea Syndrome A 2 Year Follow Up Sleep vol 36 no 9 Sept 2013 pp 1289–96 PubMed Central https://doi.org/10.5665/sleep.2948
- Source: Dieltjens Marijke and Olivier M Vanderveken Oral Appliances in Obstructive Sleep Apnea Healthcare vol 7 no 4 Nov 2019 p 141 PubMed Central https://doi.org/10.3390/healthcare7040141