Landmark Year in Sleep: Leader in Sleep and Respiratory Medicine Highlights Top Five Sleep apnoea Research Findings

SAN DIEGO, March 14, 2014 —To coincide with today’s World Sleep Day, ResMed (NYSE: RMD), an innovator and pioneer in developing solutions for treating sleep-disordered breathing and other respiratory conditions, highlights its pick for the top five research discoveries about sleep apnoea from the past year. Together, they paint an alarming picture: sleep apnoea is on the rise and linked to sudden cardiac death, slower recovery from heart attacks, cancer, and high blood pressure.

1. Sleep apnoea is linked to higher rates of cancer

Obstructive sleep apnoea (OSA) deprives the body of oxygen (also known as hypoxia), which can lead to higher rates of cancer in patients under the age of 65. OSA occurs when the throat relaxes during sleep and blocks the airway, causing a person to snore and/or stop breathing until the brain triggers a wake-up response and the body struggles to gasp for air.

[Association between Obstructive Sleep apnoea and Cancer Incidence in a large multicenter Spanish Cohort (Campos-Rodriguez et al., 2013 Am J of Respir Crit Care Med)]

2. Sleep apnoea increases risk of sudden cardiac death

“Oxygen is our lifeline,” said Adam Benjafield, Ph.D., ResMed vice president of Medical Affairs. “When our bodies are deprived of oxygen during episodes of sleep apnoea, a long list of negative health consequences can occur. The research shows that those suffering from sleep apnoea are at a greater risk of a sudden cardiac death, plain and simple.”

[Obstructive sleep apnoea and the risk of sudden cardiac death: A longitudinal study of 10,701 adults. (Gami et al., 2013 J Am Coll Cardiol.)]

3. Untreated sleep apnoea slows recovery from heart attacks

“This study is important because it demonstrates that if you have a heart attack and also have untreated sleep apnoea, your heart will not heal as effectively as the heart of someone without sleep apnoea, and recovery will be impaired,” said Benjafield.

[Impact of sleep-disordered breathing on myocardial salvage and infarct size in patients with acute myocardial infarction. (Buchner et al., 2013 Eur Heart J.)]

4: Treatment for sleep apnoea can reduce blood pressure

Treatment of sleep apnoea with continuous positive air pressure (CPAP) therapy reduces blood pressure in sleep apnoea patients. Widely accepted as the gold standard, CPAP therapy involves wearing a mask or nasal pillows system connected to a small portable airflow generator that delivers air at positive pressure, creating an air splint to keep the airway open.

[Effect of continuous positive airway pressure (CPAP) on blood pressure in patients with obstructive sleep apnoea/hypopnea. A systematic review and meta-analysis. (Fava et al., 2013 Chest)]

5: Sleep apnoea is increasing among men and women — up to 1 in 4 adults

The latest data on the prevalence of sleep apnoea in adults shows that the rates have gone up substantially over the last two decades. Among adults 30-70 years of age, it is estimated that 13 percent of men and 6 percent of women have moderate to severe sleep apnoea, compared to the earlier results (9 percent of men and 4 percent of women). In addition, the number of those with at least mild sleep apnoea has jumped for both men (26 to 34 percent) and women (13 to 17 percent).

[Increased Prevalence of Sleep-Disordered Breathing in Adults. (Peppard et al., 2013 Am J Epidemiol.)]

Together, the research findings demonstrate that untreated, sleep apnoea can severely affect quality of life, health, and mortality. Sleep apnoea continues to be strongly linked to a long list of life-threatening, chronic diseases such as cancer, stroke, heart failure, hypertension, diabetes, obesity, and coronary artery disease as these and other studies continue to reveal. Untreated sleep apnoea also has an association with depression, especially in women, and daytime drowsiness which increases the risk of accidents in the workplace and while driving.

Education remains a key obstacle to effective treatment. Studies indicate that as many as 85 percent of people who have sleep apnoea remain undiagnosed and untreated.

“It’s not just a question of more sleep,” said Benjafield. “It’s a question of better quality sleep, which translates directly to better health. The good news is that getting tested and receiving treatment for sleep apnoea is easier than ever.”

If you suspect that you or someone in your family might have sleep apnoea, talk to a doctor or medical professional. Typical symptoms include constant tiredness, poor concentration, morning headaches, depressed mood, night sweats, weight gain, lack of energy, forgetfulness, sexual dysfunction, irritability, and frequent urination at night. For more information, or to take a short sleep quiz, visit www.WakeUpToSleep.com.

About ResMed

ResMed changes lives by developing, manufacturing and distributing medical equipment for treating, diagnosing, and managing sleep-disordered breathing, COPD, and other chronic diseases. We develop innovative products and solutions to improve the health and quality of life of those who suffer from these conditions, and we work to raise awareness of the potentially serious health consequences of untreated sleep-disordered breathing. For more information on ResMed, visit www.resmed.com.