Neuromuscular disease (NMD)

NMD is a broad term that encompasses many diseases and ailments that impair the functioning of the muscles either directly via intrinsic muscle pathology, or indirectly via nerve pathology. Some NMD patients are characterized by progressive muscular impairment leading to loss of mobility, being wheelchair-bound, swallowing difficulties, respiratory muscle weakness, death from respiratory failure.

Neuromuscular disorders can be divided into rapidly progressive and slowly progressive disorders:

  • Rapidly progressive disorders are characterized by muscle impairment that worsens over months, and results in death within a few years (e.g. amyotrophic lateral sclerosis (ALS) and Duchenne muscular dystrophy (DMD) in teenagers).
  • Variable or slowly progressive disorders are characterized by muscle impairment that worsens over years and only mildly reduces life expectancy (e.g. limb girdle, facioscapulohumeral and myotonic muscular dystrophy).

 

Restrictive lung disease (RLD)

Restrictive lung disease refers to a group of thoracic deformities that result in inefficient coupling between the respiratory muscles and the thoracic cage. The disorders are usually characterized by a restrictive defect and share the potential to cause long term hypercapnic respiratory failure.1

The most common thoracic abnormality leading to respiratory failure is thoracoplasty. Scoliosis and/or kyphoscoliosis may also cause severe respiratory failure.

Ventilation for neuromuscular disease and restrictive lung disease

Ventilation for neuromuscular disease and restrictive lung disease

Treating a patient with respiratory failure caused by NMD/RLD can help alleviate some of the symptoms of poor respiration.

ResMed’s NMD/RLD solutions

ResMed is committed to improving the quality of life for neuromuscular disease and restrictive lung disease patients through the use of our home ventilation systems.

ResMed’s NMD/RLD solutions

ResMed’s NMD/RLD solutions

ResMed is committed to improving the quality of life for neuromuscular disease and restrictive lung disease patients through the use of our home ventilation systems.

References

  • 01

    Shneerson JM, Simonds AK. Noninvasive ventilation for chest wall and neuromuscular disorders. Eur Respir J. 2002; 20:480-487