ResMed’s neuromuscular disease (NMD) solutions

ResMed’s NIV solution for neuromuscular disease

ResMed is committed to improving the quality of life for NMD patients through the use of home NIV systems.

Our leak circuit and volume-assurance target are designed to reduce PtcCO2 in neuromuscular disease patients.

ResMed’s volume-assurance mode, iVAPS (intelligent Volume-Assured Pressure Support), secures target volume and alveolar ventilation by compensating for dead space ventilation. This is particularly important as patient conditions change during the night, such as when respiratory drive is impaired during rapid eye movement (REM) sleep or when the patient moves to a supine position.

Some ResMed ventilators also feature trigger sensitivity technology that can detect very weak breaths, triggering the ventilator to deliver the next breath for the patient so that breathing is not delayed.

iVAPS is available in the following ResMed devices used to treat respiratory conditions associated with NMD:

Special considerations

Ventilatory dependency is likely to increase over time with progressive neuromuscular disease. Consequently, ventilator settings may also need to be changed.

  • ResMed’s range of ventilators caters for both non-dependent and dependent patients. For extra versatility, ResMed ventilators offer both noninvasive and invasive options.
  • ResMed's advanced data collection capabilities (device and card data storage with high-resolution flow and pressure data, percentage of spontaneous breaths, AHI, volumes, respiratory rate, synchronisation details, SpO2 monitoring) and ResScan™ software allow clinicians to have detailed data for troubleshooting and monitoring patient progress.
Neuromuscular patients may also have obstructive sleep apnea (OSA).

If obstructive sleep apnea is present, EPAP needs to be titrated to overcome upper airway collapse.

  • AHI data viewed on the Stellar Info screen or via ResScan™ will help identify the need for EPAP adjustment.
  • High-resolution flow data can help titrate EPAP and identify PEEPi.
It is essential to maintain reliable breath triggering and cycling synchronisation between the patient and the device.

The Vsync leak management algorithm works in sync with the TiControl feature. Vsync monitors and compensates for leak by continuously and automatically adjusting the baseline flow, while TiControl assures a minimum and maximum inspiratory time. Trigger and cycle adjustment can also help with synchronisation.

Ventilatory adjuncts, such as mouth ventilation with a mouthpiece attached to a support on a wheelchair, can be helpful.

Several ResMed ventilators can be used with a mouthpiece.

Secretion clearance using NIV techniques.

Stellar ventilators allow clinicians to set two programs, one of which can be set to assist in secretion clearance techniques.

Battery backup gives patients extra mobility.

Stellar and Astral ventilators have internal batteries. All ResMed devices are compatible with the ResMed Power Station II, an external battery that provides up to eight* hours additional power or up to 16* hours if two batteries are connected.

During all stages of ventilation, it is vital to monitor the patient and their progress.

ResMed's advanced data management solutions (device and card data storage with high-resolution flow and pressure data, usage hours, volumes, percentage of spontaneous breaths, respiratory rate, AHI, SpO2 and synchronisation details) including ResScan software allows clinicians to have detailed data for troubleshooting and monitoring patient progress as required. Some ResMed ventilators such as Stellar can display live data (such as flow and pressure curves) as well as summary data on the device itself.

Real-time therapy monitoring allows titration of the patient, optimal follow up, and adjustment of the settings.  

*8 hours per battery at EPAP 5 cm H2O, IPAP 15 cm H2O and 20 bpm (two batteries can be connected simultaneously)

More about NMD