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NIV has been shown to improve daytime arterial blood gases and the symptoms associated with respiratory failure for NMD patients.
In Amyotrophic lateral sclerosis (ALS) patients, NIV improves quality of life and sleep-related symptoms. In patients without severe bulbar dysfunction,1 NIV prolongs survival by 7 months.
In Duchenne muscular dystrophy (DMD) patients:
Eagle M, Bourke J, Bullock R, et al. Managing Duchenne muscular dystrophy—the additive effect of spinal surgery and home nocturnal ventilation in improving survival. Neuromuscular Disorders. 2007; 17:470–5.